hua
Tetracaine hydrochloride
Taipitopito hua
MF: C15H25ClN2O2
MW: 300.82
CAS: 136-47-0
1．Tetracaine hydrochloride he rongoa rongoa a-rohe ka taea te aukati i te mahi nerve.Ka whakamahia i roto i te rewharewha urutomo, te whakamohoatanga poraka nerve, te rewharewha epidural, me etahi atu ka whakatauritea ki te procaine, he mea nui te awenga o te rewharewha o te rohe, a kua whakamahia nuitia i roto i te whare haumanu.Na roto i te ako i nga huarahi whakahiato o naianei, ka kitea ko te whakahiatotanga o te waikawa p-butylamino benzoic takawaenga ko te mahi matua i roto i te whakahiato o te tetracaine hydrochloride, kei a ia nga ngoikoretanga o nga rauemi mata korekore, he iti ranei nga hua.Kua whakapai ake nga kaiputaiao i tenei.I te tau 1981, i whakaaro ratou ki te whakahiato i te waikawa p-butylamino benzoic ma te alkylating waikawa p-aminobenzoic me te 1-Bromobutane.Heoi, na te kore e taea te hanga o nga hua o te dibutylation me te ahua koretake o nga rauemi mata, kaore tenei huarahi e pai mo te hanga ahumahi.
2．Tetracaine hydrochloride Kei te whakamahia mo te rewharewha mata mucosal, rewharewha kawe, rewharewha epidural me te rewharewha subarachnoid;Ka whakamahia mo te rewharewha o te mata o te mata, kaore e whakatiki i nga oko toto, e kore e kino te epithelium o te koo, e kore e piki te pehanga intraocular.
3．Ka taea e tenei tarukino te whakarei ake i te paanga o te paraka nerve o te cisatracurium, me whakaheke te inenga o muri ka whakakotahihia.Ka honoa ki te adrenaline, ka taea e ia te whakatiki i nga oko toto, te whakaheke i te rere o te toto, te whakaroa i te horomitanga o te raau taero, me te whakaroa i te roanga o te mahi.Engari ko te huinga o nga mea e rua e kore e pai mo nga turoro me te mate ngakau, te takawhita, te hyperthyroidism, te mate pukupuku peripheral me etahi atu.Ka taea e te Hyaluronidase te whakanui ake i te tohatoha o tenei tarukino, te whakatere i te timatanga o te mate pukupuku, te whakaiti i te pupuhi o te rohe, me te aukati i te hanganga o te hematoma.Heoi ano, ka taea ano e te hyaluronidase te tere ake te whakauru o tenei tarukino, ka hua ake te paitini o te pukapuka matū anti o tenei tarukino.Ko tenei rongoa he hua o te waikawa p-aminobenzoic (PABA).Ko nga sulfonamides he mahi antibacterial ma te aukati i te PABA o te huakita.Ina whakakotahihia tenei tarukino me te sulfonamides, ka whakakorehia te paanga antibacterial o muri, na reira kaua e whakakotahi nga mea e rua.He waikawa tenei rongoa, kaua e konatunatua ki te rongoa wai kawakore;Ahakoa nga raau taero waikawa ka pa ki te uara wehewehe o te tarukino na te rerekee o te pH, na te mea ka heke te mahi, ka whakaroa ranei te wa timatanga.Ka taea e te whakarite iodine te rerenga o tenei tarukino, na reira kaore e taea te whakamahi i te waahi werohanga o tenei tarukino.
Taupānga
Ko tenei hua he rongoa whakamaroi a-rohe ester roa.Ko ona ahuatanga mahi ko: te urunga kaha ki te mucosa, e tika ana mo te rewharewha o te mata, kaore he tauhohenga kino penei i te vasoconstriction, mydriasis, te whara o te kiore i muri i te paheketanga o te kanohi.Ka whakamahia i roto i te ophthalmology.He 10 nga wa nui atu i te procaine te awenga o te anesthetic rohe me te paitini.Whai muri i te werohanga, ka puhoi te ahua o te rongoa rongoa o te pukapuka matū (tata ki te 10 meneti), ka puhoi hoki te paopaotanga i muri i te whakaurunga.Ko te wa whakamohoatanga o te rohe ka eke ki te 3ij, h, -j.mō.Ka whakamahia te nuinga mo te rewharewha mata o te kanohi, te ihu me te korokoro mucosa, a he uaua ki te whakamahi mo te rewharewha me te rewharewha epidural.Ko te tikanga, kaore i te whakamahia mo te rewharewha whakauru na te nui o te paitini.
